*equal contribution #corresponding author
Scheduled simple production method of pseudopregnant female mice for embryo transfer using the luteinizing hormone-releasing hormone agonist
Sari GP, Hilario PLL, Yuri S, *Honda A, *#Isotani A.
Sci Rep. 2022 Dec 20;12(1):21985. doi: 10.1038/s41598-022-26425-2.
Adenovirus-mediated gene delivery restores fertility in congenitally infertile female mice.
Kanatsu-Shinohara M, Lee J, Miyazaki T, Morimoto H, #Shinohara T.
J Reprod Dev. 2022 Dec 19;68(6):369-376. doi: 10.1262/jrd.2022-090. Epub 2022 Oct 13.
Cell cycle-specific loading of condensin I is regulated by the N-terminal tail of its kleisin subunit.
Tane S, Shintomi K, Kinoshita K, Tsubota Y, Yoshida MM, Nishiyama T, # Hirano T.
Elife. 2022 Dec 13;11:e84694. doi: 10.7554/eLife.84694.
A region-dependent allele-biased expression of Dopa decarboxylase in mouse brain.
Sheng KY, Nakano T, #Yamaguchi S.
Front Cell Dev Biol. 2022 Dec 7;10:1078927. doi: 10.3389/fcell.2022.1078927.
Generation of humanized LDHC knock-in mice as a tool to assess human LDHC-targeting contraceptive drugs.
Iida-Norita R, Miyata H, Kaneda Y, Emori C, Noda T, Nakagawa T, #Matzuk MM, #Ikawa M.
Andrology. 2022 Dec 4. doi: 10.1111/andr.13359. Online ahead of print.
TDP-43 safeguards the embryo genome from L1 retrotransposition.
Li TD, #Murano K, Kitano T, Guo Y, Negishi L, #Siomi H.
Sci Adv. 2022 Nov 25;8(47):eabq3806. doi: 10.1126/sciadv.abq3806. Epub 2022 Nov 23.
紹介記事
CRISPR/Cas9-mediated disruption of lipocalins, Ly6g5b, and Ly6g5c causes male subfertility in mice.
Sakurai N, #Fujihara Y, Kobayashi K, #Ikawa M.
Andrology. 2022 Nov 25. doi: 10.1111/andr.13350. Online ahead of print.
Morphological growth dynamics, mechanical stability, and active microtubule mechanics underlying spindle self-organization.
Fukuyama T, Yan L, Tanaka M, Yamaoka M, Saito K, Ti S , Liao C, Hsia K , Maeda YT, #Shimamoto Y.
Proc Natl Acad Sci U S A. 2022 Nov;119(44):e2209053119. doi: 10.1073/pnas.2209053119. Epub 2022 Oct 25.
Mod(mdg4) variants repress telomeric retrotransposon HeT-A by blocking subtelomeric enhancers.
Takeuchi C, Yokoshi M, Kondo S, Shibuya A, Saito K, Fukaya T, #Siomi H, #Iwasaki YW.
Nucleic Acids Res. 2022 Nov 11;50(20):11580-11599. doi: 10.1093/nar/gkac1034.
紹介記事
De novo non-synonymous CTR9 variants are associated with motor delay and macrocephaly: human genetic and zebrafish experimental evidence.
Suzuki H, Aoki K, Kurosawa K, Imagawa K, Ohto T, Yamada M, Takenouchi T, #Kosaki K, #Ishitani T.
Hum Mol Genet. 2022 Nov 10;31(22):3846-3854. doi: 10.1093/hmg/ddac136.
Suppression of endogenous retroviral enhancers in mouse embryos derived from somatic cell nuclear transfer
Shikata D, Matoba S, Hada M, Sakashita A, Inoue K, #Ogura A.
Front Genet. 2022 Nov 8;13:1032760. doi: 10.3389/fgene.2022.1032760. eCollection 2022.
PDCL2 is essential for sperm acrosome formation and male fertility in mice.
#Fujihara Y, Kobayashi K, Abbasi F, Endo T, Yu Z, Ikawa M, Matzuk MM.
Andrology. 2022 Oct 24. doi: 10.1111/andr.13329. Online ahead of print.
Human sperm TMEM95 binds eggs and facilitates membrane fusion.
*Tang S, *Lu Y, Skinner WM, Sanyal M, Lishko PV, #Ikawa M, #Kim PS.
Proc Natl Acad Sci U S A. 2022 Oct 4;119(40):e2207805119. doi: 10.1073/pnas.2207805119. Epub 2022 Sep 26.
Paternally inherited H3K27me3 affects chromatin accessibility in mouse embryos produced by round spermatid injection.
Sakamoto M, Ito D, Inoue R, Wakayama S, Kikuchi Y, Yang L, Hayashi E, Emura R, Shiura H, Kohda T, Namekawa SH, #Ishiuchi T, Wakayama T, #Ooga M.
Development. 2022 Sep 15;149(18):dev200696. doi: 10.1242/dev.200696. Epub 2022 Sep 15.
Regulation of male germline transmission patterns by the Trp53-Cdkn1a pathway.
Kanatsu-Shinohara M, Naoki H, Tanaka T, Tatehana M, Kikkawa T, Osumi N, #Shinohara T.
Stem Cell Reports. 2022 Sep 13;17(9):1924-1941. doi: 10.1016/j.stemcr.2022.07.007. Epub 2022 Aug 4.
Analysis of plasmodesmata permeability using cultured tobacco BY-2 cells entrapped in microfluidic chips.
Kurotani KI, Kawakatsu Y, Kikkawa M, Tabata R, Kurihara D, Honda H, #Shimizu K, #Notaguchi M.
J Plant Res. 2022 Sep;135(5):693-701. doi: 10.1007/s10265-022-01406-8. Epub 2022 Jul 14.
Cell cycle-dependent radiosensitivity in mouse zygotes. DNA Repair (Amst).
Wang Y, Oda S, Suzuki MG, Mitani H, #Aoki F.
2022 Sep;117:103370. doi: 10.1016/j.dnarep.2022.103370. Epub 2022 Jul 6.
Histone H3K36me2 and H3K36me3 form a chromatin platform essential for DNMT3A-dependent DNA methylation in mouse oocytes.
Yano S, #Ishiuchi T, Abe S, Namekawa S, Huang G, Ogawa Y & #Sasaki H.
Nat Commun 13, 4440 (2022). https://doi.org/10.1038/s41467-022-32141-2.
紹介記事
Molecular dissection of condensin II-mediated chromosome assembly using in vitro assays.
Yoshida MM, Kinoshita K, Aizawa Y, Tane S, Yamashita D, Shintomi K, # Hirano T.
Elife. 2022 Aug 19;11:e78984. doi: 10.7554/eLife.78984.
IRGC1, a testis-enriched immunity related GTPase, is important for fibrous sheath integrity and sperm motility in mice.
Kaneda Y, #Miyata H, Shimada K, Oyama Y, Iida-Norita R, #Ikawa M.
Dev Biol. 2022 Aug;488:104-113. doi: 10.1016/j.ydbio.2022.05.011. Epub 2022 May 23.
Dynamic changes of intracellular zinc ion level during maturation, fertilization, activation, and development in mouse oocytes
Atsuko Kageyama, Ayumi Suyama, Ruka Kinoshita, #Junya Ito, Naomi Kashiwazaki.
Anim Sci J. 2022 Jan-Dec;93(1):e13759. doi: 10.1111/asj.13759.
Healthy cloned offspring derived from freeze-dried somatic cells.
#Wakayama S, Ito D, Hayashi E, Ishiuchi T, #Wakayama T.
Nat Commun. 2022 Jul 5;13(1):3666. doi: 10.1038/s41467-022-31216-4.
Involvement of the linker histone H1Foo in the regulation of oogenesis. Reproduction.
Funaya S, Kawabata Y, Sugie K, Abe KI, Suzuki Y, Suzuki MG, #Aoki F.
2022 Jun 23;164(2):19-29. doi: 10.1530/REP-21-0233.
The microRNA cluster C19MC confers differentiation potential into trophoblast lineages upon human pluripotent stem cells.
Kobayashi N, #Okae H, Hiura H, Kubota N, Kobayashi EH, Shibata S, Oike A, Hori T, Kikutake C, Hamada H, Kaji H, Suyama M, Bortolin-Cavaillé ML, Cavaillé J, #Arima T.
Nat Commun. 2022 Jun 2;13(1):3071. doi: 10.1038/s41467-022-30775-w.
紹介記事
Trim41 is required to regulate chromosome axis protein dynamics and meiosis in male mice.
Oura S, Hino T, Satoh T, Noda T, Koyano T, Isotani A, Matsuyama M, Akira S, Ishiguro KI, #Ikawa M.
PLoS Genet. 2022 Jun 1;18(6):e1010241. doi: 10.1371/journal.pgen.1010241. eCollection 2022 Jun.
TULP2 deletion mice exhibit abnormal outer dense fiber structure and male infertility.
Oyama Y, #Miyata H, Shimada K, Larasati T, Fujihara Y, #Ikawa M
Reprod Med Biol. 2022 May 23;21(1):e12467. doi: 10.1002/rmb2.12467. eCollection 2022 Jan-Dec.
Birth of mice from meiotically arrested spermatocytes following biparental meiosis in halved oocytes.
Ogonuki N, Kyogoku H, Hino T, Osawa Y, Fujiwara Y, Inoue K, Kunieda T, Mizuno S, Tateno H, Sugiyama F, #Kitajima TS, #Ogura A.
EMBO Rep. 2022 Jul 5;23(7):e54992. doi: 10.15252/embr.202254992. Epub 2022 May 19.
紹介記事
Adeno-associated-virus-mediated gene delivery to ovaries restores fertility in congenital infertile mice.
Kanatsu-Shinohara M, Lee J, Miyazaki T, Morimoto H, #Shinohara T.
Cell Rep Med. 2022 May 17;3(5):100606. doi: 10.1016/j.xcrm.2022.100606. Epub 2022 Apr 27.
Pramef12 enhances reprogramming into naïve iPS cells.
Haraguchi D, #Nakamura T.
Biochem Biophys Rep. 2022 May 10;30:101267. doi: 10.1016/j.bbrep.2022.101267.
Single-cell profiling of transcriptomic changes during in vitro maturation of human oocytes.
Takeuchi H, Yamamoto M, Fukui M, Inoue A, Maezawa T, Nishioka M, Kondo E, Ikeda T, Matsumoto K, #Miyamoto K.
Reprod Med Biol. 2022 May 9;21(1):e12464. doi: 10.1002/rmb2.12464.
Regeneration of spermatogenesis by mouse germ cell transplantation into allogeneic and xenogeneic testis primordia or organoids.
Kanatsu-Shinohara M, Ogonuki N, Matoba S, Morimoto H, Shiromoto Y, Ogura A, #Shinohara T.
Stem Cell Reports. 2022 Apr 12;17(4):924-935. doi: 10.1016/j.stemcr.2022.02.013. Epub 2022 Mar 24.
Functional primordial germ cell-like cells from pluripotent stem cells in rats.
Oikawa M, Kobayashi H, Sanbo M, Mizuno N, Iwatsuki K, Takashima T, Yamauchi K, Yoshida F, Yamamoto T, Shinohara T, Nakauchi H, Kurimoto K, #Hirabayashi M, #Kobayashi T.
Science. 2022 Apr 8;376(6589):176-179. doi: 10.1126/science.abl4412. Epub 2022 Apr 7.
Noncanonical imprinting sustains embryonic development and restrains placental overgrowth.
Matoba S, Kozuka C, Miura K, Inoue K, Kumon M, Hayashi R, Ohhata T, Ogura A, #Inoue A.
Genes Dev. 2022 Apr 1;36(7-8):483-494. doi: 10.1101/gad.349390.122. Epub 2022 Apr 28.
紹介記事
Photo-isolation chemistry for high-resolution and deep spatial transcriptome with mouse tissue sections.
Honda M, Kimura R, Harada A, Maehara K, Tanaka K, #Ohkawa Y, #Oki S.
STAR Protoc. 2022 Apr 22;3(2):101346. doi: 10.1016/j.xpro.2022.101346.
Development of microfluidic chip for entrapping tobacco BY-2 cells.
#Shimizu K, Kawakatsu Y, Kurotani KI, Kikkawa M, Tabata R, Kurihara D, Honda H, #Notaguchi M.
PLoS One. 2022 Apr 14;17(4):e0266982. doi: 10.1371/journal.pone.0266982.
Nuclear transfer system for the direct induction of embryonic transcripts from intra- and cross-species nuclei using mouse 4-cell embryos.
Tomikawa J, Penfold CA, Hatakeyama R, #Miyamoto K.
STAR Protoc. 2022 Apr 11;3(2):101284. doi: 10.1016/j.xpro.2022.101284
Sperm membrane proteins DCST1 and DCST2 are required for sperm-egg interaction in mice and fish.
Noda T, Blaha A, Fujihara Y, Gert KR, Emori C, Deneke VE, Oura S, Panser K, Lu Y, Berent S, Kodani M, Cabrera-Quio LE, #Pauli A, #Ikawa M.
Commun Biol. 2022 Apr 7;5(1):332. doi: 10.1038/s42003-022-03289-w.
Use of anti-inhibin monoclonal antibody for increasing the litter size of mouse strains and its application to in vivo-genome editing technology†.
Hasegawa A, #Mochida K, Nakamura A, Miyagasako R, Ohtsuka M, Hatakeyama M, #Ogura A.
Biol Reprod. 2022 Aug 9;107(2):605-618. doi: 10.1093/biolre/ioac068.
Zebrafish imaging reveals TP53 mutation switching oncogene-induced senescence from suppressor to driver in primary tumorigenesis.
Haraoka Y, Akieda Y, Nagai Y, Mogi C, #Ishitani T.
Nat Commun. 2022 Mar 18;13(1):1417. doi: 10.1038/s41467-022-29061-6.
Conservation and divergence of canonical and non-canonical imprinting in murids.
#Richard Albert J, Kobayashi T, Inoue A, Monteagudo-Sánchez A, Kumamoto S, Takashima T, Miura A, Oikawa M, Miura F, Takada S, Hirabayashi M, Korthauer K, Kurimoto K, Greenberg MVC, Lorincz M, #Kobayashi H.
Genome Biol. 2023 Mar 14;24(1):48. doi: 10.1186/s13059-023-02869-1.
Uterus-specific transcriptional regulation underlies eggshell pigment production in Japanese quail.
Ishishita S, Kitahara S, Takahashi M, Iwasaki S, Tatsumoto S, Hara I, Kaneko Y, Kinoshita K, Yamaguchi K, Harada A, Ohmori Y, Ohkawa Y, Go Y, Shigenobu S, Matsuda Y, #Suzuki T.
PLoS One. 2022 Mar 10;17(3):e0265008. doi: 10.1371/journal.pone.0265008.
A loop extrusion-independent mechanism contributes to condensin I-mediated chromosome shaping.
Kinoshita K, Tsubota Y, Tane S, Aizawa Y, Sakata R, Takeuchi K, Shintomi K, Nishiyama T, #Hirano T.
J Cell Biol. 2022 Mar 7;221(3):e202109016. doi: 10.1083/jcb.202109016. Epub 2022 Jan 19.
The motor domain of testis-enriched kinesin KIF9 is essential for its localization in the mouse flagellum.
#Miyata H, Oyama Y, Kaneda Y, #Ikawa M.
Exp Anim. 2022 Feb 9;71(1):46-52. doi: 10.1538/expanim.21-0082. Epub 2021 Sep 15.
Establishment of mouse stem cells that can recapitulate the developmental potential of primitive endoderm.
#Ohinata Y, Endo TA, Sugishita H, Watanabe T, Iizuka Y, Kawamoto Y, Saraya A, Kumon M, Koseki Y, Kondo T, Ohara O, Koseki H.
Science. 2022 Feb 4;375(6580):574-578. doi: 10.1126/science.aay3325. Epub 2022 Feb 3.
紹介記事
TFB2M and POLRMT are essential for mammalian mitochondrial DNA replication.
Inatomi T, Matsuda S, Ishiuchi T, Do Y, Nakayama M, Abe S, Kasho K, Wanrooij S, Nakada K, Ichiyanagi K, Sasaki H, #Yasukawa T, Kang D.
Biochim Biophys Acta Mol Cell Res. 2022 Jan;1869(1):119167. doi: 10.1016/j.bbamcr.2021.119167. Epub 2021 Oct 30.
C2cd6-encoded CatSperτ targets sperm calcium channel to Ca2+ signaling domains in the flagellar membrane.
Hwang JY, Wang H, Lu Y, Ikawa M, #Chung JJ.
Cell Rep. 2022 Jan 18;38(3):110226. doi: 10.1016/j.celrep.2021.110226. Epub 2022 Jan 7.
Optical Clearing of Plant Tissues for Fluorescence Imaging.
#Kurihara D, Mizuta Y, Nagahara S, Sato Y, Higashiyama T.
J Vis Exp. 2022 Jan 5;(179). doi: 10.3791/63428.
Highlyrigid H3.1/H3.2-H3K9me3 domains set a barrier for cell fate reprogramming in trophoblast stem cells.
Hada M, Miura H, Tanigawa A, Matoba S, Inoue K, Ogonuki N, Hirose M, Watanabe N, Nakato R, Fujiki K, Hasegawa A, Sakashita A, Okae H, Miura K, Shikata D, Arima T, Shirahige K, Hiratani I, #Ogura A.
Genes Dev. 2022 Jan 1;36(1-2):84-102. doi: 10.1101/gad.348782.121. Epub 2022 Jan 6.
紹介記事
Dynamic modulation of enhancer responsiveness by core promoter elements in living Drosophila embryos.
Yokoshi M, Kawasaki K, Cambón M, #Fukaya T.
Nucleic Acids Res. 2022 Jan 11;50(1):92-107. doi: 10.1093/nar/gkab1177.
紹介記事
*equal contribution #corresponding author